Neutrophilic-chronic myeloid leukemia
نویسندگان
چکیده
منابع مشابه
Neutrophilic-chronic myeloid leukemia: A case report.
Neutrophilic-chronic myelogenous leukemia (CML-N) is a rare chronic myelogenous leukemia (CML) variant characterized by BCR-ABL1 positive chronic neutrophilia. It has a BCR breakpoint on chromosome 22 between exons 17 and 20 in a region designated as micro-BCR. It is thought to have a more benign course than classical CML. This case report describes a 41-year-old Saudi woman diagnosed with CML-...
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According to the 2008 World Health Organization classification, chronic neutrophilic leukemia, chronic myelomonocytic leukemia and atypical chronic myeloid leukemia are rare diseases. The remarkable progress in our understanding of the molecular genetics of myeloproliferative neoplasms and myelodysplastic/myeloproliferative neoplasms has made it clear that there are some specific genetic abnorm...
متن کاملSpecific molecular mutation patterns delineate chronic neutrophilic leukemia, atypical chronic myeloid leukemia, and chronic myelomonocytic leukemia.
Chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML) are rare entities grouped into the World Health Organisation (WHO) categories myeloproliferative and myelodysplastic/myeloproliferative neoplasms (MPN and MDS/MPN overlap), respectively. According to the WHO 2008 classification, both entities are characterized by leukocytosis and a hypercellular bone marrow, predom...
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All patients received the first plasma exchange employing fresh frozen plasma, and CPP was used in the following procedures. PE was performed daily until normalization of the platelet count and serum LDH levels. Two patients (B.S. and P.M.L.) died 8 and 5 days, respectively, after beginning plasma exchange, and the addition of highdose iv immunoglobulins in one case did not produce any effect. ...
متن کاملClonality of chronic neutrophilic leukemia.
Kwong and Cheng’ recently reported a case of chronic neutrophilic leukemia (CNL) with absence of Philadelphia (Ph) chromosome and no bcr rearrangement. They showed the clonal nature of CNL by the methylation status of the X-linked hypoxanthine phosphoribosyl transferase. (HPRT) gene. The clonal myeloproliferative nature of CNL was first documented in our report of a case of polycythemia vera (P...
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ژورنال
عنوان ژورنال: Cancer
سال: 2002
ISSN: 0008-543X,1097-0142
DOI: 10.1002/cncr.10490